The model, which simulates every NFL game 10,000 times, is up more than $7,000 for $100 players on top-rated NFL picks since its inception. Bills picks or NFL predictions, you need to see the NFL betting advice from the SportsLine Projection Model. Buccaneers odds while the over/under for total points scored is 43.5. Buffalo is a 9.5-point favorite in the latest Bills vs. Buccaneers receiver Chris Godwin (neck) and quarterback Baker Mayfield (knee) are both active for Thursday Night Football. The Bills are coming off a 29-25 loss to New England. Meanwhile, after blowing out three straight opponents, Buffalo (4-3) has played in three straight one-score games, losing two of them. The Buccaneers trail the Falcons by a half-game in the NFC South standings. Tampa Bay (3-3) has lost back-to-back home games to Detroit and Atlanta and three of its last four overall. Two teams looking for answers will collide when the Buffalo Bills and Tampa Bay Buccaneers meet on Thursday Night Football.